I think the worst case would be dealing with mass numbers of poeple that is intent on ridding you of your preps (food)
The masses scare easily. A few dead, and they lose their stomach for it.
The greater concern, will be any gangs made up of, and led by, former military, etc. These guys will be trained marksmen, tacticians, etc.
Against a good number of these folks, our plan is likely going to be to run or make a deal. Personally, I'd rather make a resupply deal with them...with them recognizing they won't have the skills to keep replenishable food and water going, replenishable medicinals, etc., but in exchange for some scrounged items and peace, we could provide these.
A lot would depend on how they approached. If openly, we may talk. If not, and in a more offensive position, we'll likely do plan B....run and wait them out. I say wait them out, because they'll succumb to some presents we'll leave behind, so within a week or so, we'll just have to pick off any survivors, and clean up the bodies, repair any damage, etc.
The even bigger danger though, is the same type of gang, although led by someone who doesn't really consider the future. This guy may kill all the animals for food, not considering that a chicken lays eggs each day, etc., and may even burn the place down if we leave. These are the kinds of folks that would keep me up at night.