The straight up answer is that you may be able to talk to your next door neighbor but not the house on the other side of them. None of these radios will follow curve of the earth, so they are limited to 6 miles (potential) with no trees, buildings or other obstructions. More power will help "push" though some obstructions like buildings and trees, but with the useless antenna on EACH and EVERY FRS approved radio, you will be lucky to get more than your next door neighbor if both are indoors. I use these radios for running trip-wire sensors and motion detector sensors on likely approach routes, but the range is very limited.
A pure GMRS radio (if you can find one), allows replaceable antenna, but any radio that includes FRS approval or "Type Acceptance" must, by law, have a non-removeable antenna that is deliberately stunted in the ability to resonate or radiate at the transmitter frequencies. The biggest problem I have with these walkie talkies (even if I could find one that is purely GMRS, is they cost more than a HAM radio. It may not be entirely legal to transmit with your UV5R or Wouxun KG-UV8D radio on MURS, GMRS frequencies, but it has the capability. In fact, most of the little HAM dual bander HT radios will transmit on commmercial and public service frequencies as well if you configure them to.